UNDER THE HOOD
Right now, more than 40,000 people nationwide are in line for a new kidney. During the several years they'll wait for a donor organ, patients must be hooked up to a machine that cleans and filters their blood. Dialysis, the most common process, and hemofiltration, a variation, scrub the blood but, unlike real kidneys, can't selectively reclaim the salts, sugars, and water that the body needs to thrive. Without these nutrients, the patient's chances of long-term survival are greatly reduced.
Using living renal cells from the kidneys of pigs, David Humes, a researcher at the Veterans Affairs Medical Center in Ann Arbor, Michigan, has built a bioartificial kidney that helps the body reclaim the nutrients dialysis drains away. The foot-long Renal Assist Device, below, has worked on dogs; Humes is hoping for FDA approval to begin human trials later this year. His goal is a bioartificial organ that can be worn clipped to a belt. The device, Humes predicts, could reduce dialysis time by up to 50 percent, and may even replace transplants entirely.
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